Bufo alvarius, also known as the Colorado River toad or the Sonoran Desert toad, secretes a milky-white substance from its parotid glands that contains 5-MeO-DMT, a powerful psychedelic compound. When dried and smoked, this secretion can induce an intense, short-lived psychedelic experience characterized by vivid hallucinations, altered perceptions, and a strong sense of euphoria or interconnectedness. The effects typically last 15-30 minutes.